Toroidal-Spiral Particles Heading link
Toroidal-Spiral Particles
Toroidal-spiral particles droplet sedimentation kinetics and interaction Heading link
When a polymer droplet sediments in a miscible solution, viscous forces overwhelm any small miscible interfacial tension existing between the polymer and the bulk solutions to roll up the interface into an intricate toroidal-spiral shape. This heterogeneous structure, whose length and width can be precisely manipulated by tuning the fluid dynamic parameters, presents a large surface-to-volume ratio.
Co-encapsulation and delivery of antibodies and small molecular drugs Heading link
The release schedule of the compounds can be independently manipulated to reach the best drug synergy.
Therapeutic cell delivery Heading link
The toroidal-spiral particles are designed for in vivo cell expansion and delivery.
Nanoparticle Heading link
Nanoparticle
Scalable, continuous process to generate nanoparticles with well-controlled physicochemical and biomedical properties Heading link
The nanoparticles are designed with cooperative features for better treatment of complex diseases.
These biocompatible and biodegradable nanoparticles are synthesized with a narrow size distribution, high drug loading, and long-term stability.
Advanced X-ray techniques Heading link
Advanced X-ray techniques
Integration of microfluidic devices with synchrotron X-ray for the in situ detection of ultra-fast self-assembly kinetics Heading link
Utilizing synchrotron small-angle X-ray scattering (SAXS) integrated with a microfluidic device, micellization kinetics of a diblock co-polymer, poly(ethylene glycol)-b-poly(caprolactone), was measured in situ with millisecond temporal and micrometer spatial resolution
Molecular packing, binding, and degradation at the gas/water interface Heading link
We investigated molecular packing, interaction, and degradation of phospholipids and enzymes using X-ray reflectivity and grazing incidence X-ray diffraction (GIXD) techniques. After enzyme-catalyzed degradation of saturated phospholipids, fatty acids together with divalent cations self-assembled into highly ordered inverted bilayer and trilayer structures.